A Comparative Analysis of Subtilisin-like Cuticle-degrading Proteases (Pr1)

A comparative analysis of subtilisin-like cuticle-degrading proteases (Pr1) from Beauveria bassiana and Beauveria brongniartii: an in-silico approach

My project focused on a comparative in silico analysis of subtilisin-like cuticle-degrading proteases (Pr1) from the entomopathogenic fungi Beauveria bassiana and Beauveria brongniartii. The objective was to identify, classify, and characterize proteases at the phylogenetic, physicochemical, and structural levels, and to evaluate their interactions with potential peptide ligands by applying molecular docking. This research improves our understanding of fungal virulence mechanisms and provides insights for the development of more effective, sustainable fungal-based biocontrol agents for pest management.