Analysis of the Phenotypic Characteristics of Human Islets and Their Effects on Islet Functionality

The IIDP has created and maintained the current largest dataset for human islets derived from organ donations. This project was conducted in order to explore any insights or trends within the phenotypic data derived from the HIPP team, using exploration data analysis methods. This research endeavor has provided a breakdown of the donor demographics, islet spatial architecture, functionality characteristics, etc. of more than ~800 human islet donors with and without Type-2 diabetes. The objective of this project was to provide a sense of understanding and foundational comprehension of the diverse data pool currently available.