Review of Strategies for the Optimization of mRNA-LNP Manufacturing for Commercial Scalability
Program: Applied Biotechnology Master's Degree — Research and Development
Host Company: Moderna
Location: Norwood, Massachusetts (remote)
Student: Jeremy Maillet
Scaling up mRNA-LNP manufacturing from laboratory and clinical settings to commercial production presents significant challenges. These challenges entail maintaining consistent product quality and process performance. This review provides a comprehensive analysis of current strategies employed to optimize mRNA-LNP manufacturing for commercial scalability along with the current challenges and next steps.